Are FEMA flavor safety reviews since 1960 as strict as FDA's?

"GRAS evaluation of flavoring substances by the Expert Panel of FEMA (1991)"

"Criteria employed by the expert panel of fema for the gras evaluation of flavouring substances (1977)"

"The Food Additive Amendments of 1958 prompted the flavor industry to establish in 1960 an Expert Panel of the Flavor and Extract Manufacturers Association, or FEMA, an organization that has administered the GRAS program for flavors on behalf of the industry for over 40 years."

"C-10 Massoia lactone has been designated as Generally Recognized As Safe (GRAS) by the Flavor and Extract Manufacturers Association (FEMA); however, its regulatory review remains in progress."

"applies a scientific procedure published in 2005 and updated in 2018"

"with the Flavour and Extract Manufacturers Association (FEMA) GRAS list recently including compounds derived from non-native plants such as Osmanthus absolute (FEMA No. 3750) and Jambu oleoresin (FEMA No. 3783)."

"exhibiting minimal safety risks when used under regulated conditions"

"For each congeneric group, an evaluation based on the estimated intake is conducted using the conservative Threshold of Toxicological Concern (TTC) approach"

"Using a group approach that relies on a complete chemical characterization of the NFC intended for commerce, the constituents of each NFC are organized into well-defined congeneric groups and the estimated intake of each constituent congeneric group is evaluated using the conservative threshold of toxicological concern (TTC) concept."

"The Flavor and Extract Manufacturers Association (FEMA) has granted GRAS status to many volatile oils, although this assessment was based on their use as flavoring agents."

"Thirty-five NFCs, derived from the Angelica, Abies, Cananga, Croton, Apium, Canarium, Erigeron, Ferula, Zingiber, Humulus, Juniperus, Cistus, Commiphora, Boswellia, Piper, Pinus and Schinus genera were determined/affirmed as generally recognized as safe (GRAS)"

"naturally occurring substances required only to meet the general safety standard that they do not "ordinarily render [food] injurious to health" (21 CFR 172.30), while additives face more stringent requirements."

"The scope of the safety evaluation of the NFCs contained herein does not include added use in dietary supplements or any products other than food."

"were affirmed as generally recognized as safe (GRASa) under their conditions of intended use as flavor ingredients"

"The FEMA GRAS Panel, which has existed since 1960, has recognized many ingredients as GRAS (over 2000)."

"This safety evaluation is part of a series of evaluations of NFCs for use as flavoring ingredients conducted by the Expert Panel"

"an expert panel evaluates published literature, together with experimental toxicology, metabolism, and safety data and determines whether a compound is"

"Smith RL, Cohen SM, Doull J, Feron VJ, Goodman JI, et al. 2005. A procedure for the safety evaluation ofnatural flavor complexes used as ingredients in food: essential oils FoodChemToxicol 43:345–63"

"which we expect will take 18 to 24 months and which is less expensive than the alternative of filing a food additive petition with the FDA, which can take eight years or more."

"Redpoint Bio joined FEMA as a participating member in May 2005 and has experience with the GRAS determination process."